In just the first month of the 2020 pandemic, the use of antianxiety medications increased by 34 percent among Americans, according to pharmaceutical surveys. Because select serotonin reuptake inhibitors (SSRI) in particular tend to lose their effectiveness over time, some sufferers may take heart in a new study in Current Clinical Pharmacology. Iranian researchers gave one gram of ashwagandha root extract (Withania somnifera) each day for six weeks to 22 patients with generalized anxiety disorder and a placebo to a second group of 18. People in both groups were also put on SSRIs. Anxiety scores for the ashwagandha group improved by week two and kept improving during the study, significantly outperforming the scores of the control group. The extract was considered safe and free of side effects.